Intervention Summary
Preschool PTSD Treatment (PPT)
         Preschool PTSD Treatment (PPT) is a 12-session individual psychotherapy intervention that uses cognitive behavioral therapy (CBT) techniques to treat 3- to 6-year-old children with posttraumatic stress symptoms. The protocol is applicable to all types of traumatic events. PPT sessions are conducted one on one with each child, but caregivers are encouraged to participate by observing the sessions, either from another room using a video monitor or in person. PPT begins with a psychoeducation session in which the therapist and child discuss the concept of posttraumatic stress disorder (PTSD) and expectations for the remaining sessions. The second session is used to develop a discipline plan for oppositional behavior, in recognition of the comorbidity of oppositional defiant disorders with PTSD in very young children. The third session is used to practice the skills of identifying emotions. In the fourth session, therapists teach children three relaxation techniques. In the fifth session, children recount the narrative of their most distressing experience. Sessions 6 through 10 are used to expose the children to anxiety-provoking stimuli with drawings, mental imagery, and in vivo homework. In session 11, children are taught to deal with future distressing situations. Session 12 is used to review and consolidate autobiographical narratives.  Caregivers' participation in PPT is designed to help them learn the material simultaneously with their children and increase their attunement to their children's issues. Caregivers also spend time alone with the therapists to help the therapists interpret the children's expressions and to discuss homework. All sessions are 45-60 minutes in duration and are delivered by licensed, trained mental health clinicians. It is optimal if the clinicians have some experience delivering CBT and working with young children.  In the study reviewed for this summary, the participants were children who had experienced a life-threatening traumatic event, were between 36 and 83 months old at the time of the most recent trauma, and had four or more PTSD symptoms, including reexperiencing or avoidance. The majority of participants initially recruited for the study were 3- to 6-year-olds who had experienced acute single-blow trauma (recruited from a Level I trauma center) or chronic repeated events (recruited through battered women's programs). The study also included children who had experienced trauma related to the Hurricane Katrina disaster.  
                            The documents below were reviewed for Quality of Research. The research point of
                            contact can provide information regarding the studies reviewed and the availability
                            of additional materials, including those from more recent studies that may have been conducted. Scheeringa, M. S., Weems, C. F., Cohen, J. A., Amaya-Jackson, L., & Guthrie, D. Trauma-focused cognitive-behavioral therapy for posttraumatic stress disorder in three through six year-old children: A randomized clinical trial. Journal of Child Psychology and Psychiatry, 52(8), 853-860.   Egger, H. L., Erkanli, A., Keeler, G., Potts, E., Walter, B. K., & Angold, A. Test-retest reliability of the Preschool Age Psychiatric Assessment (PAPA). Journal of the American Academy of Child Adolescent Psychiatry, 45(5), 538-549.   
                            The following populations were identified in the studies reviewed for Quality of
                            Research. 
                            External reviewers independently evaluate the Quality of Research for an intervention's
                            reported results using six criteria: 
                            For more information about these criteria and the meaning of the ratings, see Quality of Research.
                         The outcome measure used in the study has strong psychometric properties. Attention was paid to assessing fidelity of the intervention. Therapists received extensive training and met with the principal investigator weekly during the study to watch their most symptomatic interviews on videotape to monitor for drift, critique technique, and correct coding errors. A treatment fidelity checklist was completed by therapists after every session. The four therapists' self-rated fidelity scores ranged from 93% to 97.5%. An independent rater scored 30.7% of the treatment sessions by reviewing videotapes and agreed with the therapists' self-ratings 97.1% of the time. Attrition rates were was high. One significant confounding variable is the effect of Hurricane Katrina, which occurred 5 months after the start of the study and forced the suspension of activities for 6 months. Because some participants could not be located after the storm, the study design was modified so that not all participants were randomized as planned. The study had a small sample size that may not have yielded enough statistical power, leading to the possibility that findings may be inconclusive. 
                                The materials below were reviewed for Readiness for Dissemination. The implementation
                                point of contact can provide information regarding implementation of the intervention
                                and the availability of additional, updated, or new materials. Other materials:  
                                    External reviewers independently evaluate the intervention's Readiness for Dissemination
                                    using three criteria: For more information about these criteria and the meaning of the ratings, see Readiness for Dissemination.
                                 The treatment manual is easy to follow and written in user-friendly language. The treatment manual and all other program materials can be downloaded from the program Web site at no cost to implementers. The treatment manual clearly defines the target audience and identifies the conditions and situations in which this intervention should not be used. It also provides guidance on how to build rapport with clients (both children and their caregivers) and what to do if a child enrolled in the program experiences additional trauma once treatment has begun. Several checklists to support program fidelity are available. Posttraining support is available through optional phone and email consultation. There is no overview document to introduce implementers to the intervention and describe how the program materials should be used. The content and level of support offered after training is unclear. Although there are several tools to support fidelity, there is no written guidance on how to administer the tools and how the information should be used to improve program delivery. 
                The cost information below was provided by the developer. Although this cost information
                may have been updated by the developer since the time of review, it may not reflect
                the current costs or availability of items (including newly developed or discontinued
                items). The implementation point of contact can provide current information and
                discuss implementation requirements. Descriptive Information
        
    
             
        
                Areas of Interest
             
            
                Mental health treatment
             
        
             
        
                Outcomes
             
            
                  
        
1: PTSD symptoms
            
             
        
                Outcome Categories
             
            
                Mental health 
        
Trauma/injuries
            
             
        
                Ages
             
            
                0-5 (Early childhood) 
        
6-12 (Childhood)
            
             
        
                Genders
             
            
                Male 
        
Female
            
             
        
                Races/Ethnicities
             
            
                Black or African American 
        
White
Race/ethnicity unspecified
            
             
        
                Settings
             
            
                Outpatient
             
        
             
        
                Geographic Locations
             
            
                Urban
             
        
             
        
                Implementation History
             
            
                Preschool PTSD Treatment was first implemented at Tulane University. It has since been implemented in approximately 20 sites in the United States and in London, England.
             
        
             
        
                NIH Funding/CER Studies
             
            
                Partially/fully funded by National Institutes of Health: Yes 
        
Evaluated in comparative effectiveness research studies: No
            
             
        
                Adaptations
             
            
                No population- or culture-specific adaptations of the intervention were identified by the developer.
             
        
             
        
                Adverse Effects
             
            
                In the study reviewed for this summary (Scheeringa, Weems, Cohen, Amaya-Jackson, & Guthrie), among 46 children who attended at least 1 treatment session, there were 2 reports of possible adverse effects. A 5-year-old female reported on a brief Adverse Events Checklist during session 4 that her preexisting fear of the dark had worsened, but the phobia disappeared by session 8. A 6-year-old female developed enuresis (bed-wetting) by session 4, but the enuresis stopped by session 8.
             
        
             
    
                IOM Prevention Categories
             
            
                IOM prevention categories are not applicable.
             
        
    
    
     
    
     
    
              
        
                 
              
                  
                   
                      Documents Reviewed
                        Study 1
Supplementary Materials 
Outcomes
                       
                                    
                        
                                         
                                    Outcome 1: PTSD symptoms 
                                    
                                         
                                    
                                            Description of Measures
                                         
                                        
                                            Children's PTSD symptoms were assessed using the Preschool Age Psychiatric Assessment (PAPA), a structured interview used to diagnose psychiatric disorders in preschool children (ages 2-5). Derived from the Child and Adolescent Psychiatric Assessment, which is used with older children, the PAPA is tailored to feelings and behaviors pertinent to younger children. The PAPA has 26 sections focusing on a range of issues (e.g., play and peer and sibling relationships; elimination issues; sleep behaviors; separation anxiety; reactive attachment; PTSD, etc.). The PTSD section includes items dealing with acute reaction, intrusive recollections, nightmares, dissociative experiences, detachment or estrangement, and irritability. In the study, this measure was administered to caregivers by trained interviewers. 
                                         
                                    
                                         
                                    
                                            Key Findings
                                         
                                        
                                            Participants in the study were 3- to 6-year-olds who were randomly assigned to the intervention group or to a 12-week wait-list control group. From pre- to posttest, mean scores on the PAPA in the intervention group showed substantial improvement in PTSD symptoms, whereas the control group had only slight improvement of PTSD symptoms (p < .005). This finding was associated with a large effect size (Cohen's d = 1.48). 
                                         
                                    
                                         
                                    
                                            Studies Measuring Outcome
                                         
                                        
                                            Study 1
                                         
                                    
                                         
                                    
                                            Study Designs
                                         
                                        
                                            Experimental
                                         
                                    
                                         
                                
                                            Quality of Research Rating
                                         
                                        
                                            2.8
                                            (0.0-4.0 scale)
                                         
                                    Study Populations
                        
                                
                        
                                     
                                        
                                        Study
                                     
                                    
                                        Age
                                     
                                    
                                        Gender
                                     
                                    
                                        Race/Ethnicity
                                     
                                
                                             
                            
                                                
                                                    Study 1
                                                
                                             
                                            
                                                0-5 (Early childhood) 
                                            
6-12 (Childhood)
                                            
                                                66% Male 
                                            
34% Female
                                            
                                                59.5% Black or African American 
                                        
35.1% White
5.4% Race/ethnicity unspecified
                                            
                            Quality of Research Ratings by Criteria (0.0-4.0 scale)
                        
                                    
                            
                        
                                 
                                    
                                    Outcome
                                 
                                
                                    Reliability 
                                
                                    of Measures
                                
                                    Validity 
                                
                                    of Measures
                                
                                    Fidelity
                                 
                                
                                    Missing 
                                
                                    Data/Attrition
                                
                                    Confounding 
                                
                                    Variables
                                
                                    Data 
                                
                                    Analysis
                                
                                    Overall 
                            
                                    Rating
                                
                                         
                        
                                            1: PTSD symptoms
                                         
                                        
                                            3.5
                                         
                                        
                                            3.3
                                         
                                        
                                            3.3
                                         
                                        
                                            2.0
                                         
                                        
                                            2.0
                                         
                                        
                                            2.5
                                         
                                        
                                            
                                                2.8
                                         
                                    Study Strengths 
Study Weaknesses 
     
                     
        
                 
            
                    
                                Materials Reviewed
                            
                                    Readiness for Dissemination Ratings by Criteria (0.0-4.0 scale)
                                
                                    
                                    
                            
                                         
                                            
                                            Implementation
                                             
                                        
                                            Materials
                                        
                                            Training and Support
                                             
                                        
                                            Resources
                                        
                                            Quality Assurance
                                             
                                        
                                            Procedures
                                        
                                            Overall
                                             
                                    
                                            Rating
                                        
                                                 
                                
                                                    3.3
                                                 
                                                
                                                    2.8
                                                 
                                                
                                                    2.5
                                                 
                                                
                                                
                                                    2.8
                                                 
                                            Dissemination Strengths 
 Dissemination Weaknesses 
 
     
                
           
                     
                        
                        Item Description
                     
                    
                        Cost
                     
                    
                        Required by Developer
                     
                
                             
                        
                                Preschool PTSD Treatment Manual
                             
                            
                                Free
                             
                            
                                Yes
                             
                        
                             
                        
                                2-day, on-site training for up to 15 participants
                             
                            
                                $2,500 plus travel expenses
                             
                            
                                No
                             
                        
                             
                        
                                Phone and email consultation
                             
                            
                                $150 per hour
                             
                            
                                No
                             
                        
                             
                        
                                Diagnostic Infant and Preschool Assessment
                             
                            
                                Free
                             
                            
                                No
                             
                        
                             
                        
                                Diagnostic Infant and Preschool Assessment Manual
                             
                            
                                Free
                             
                            
                                No
                             
                        
                             
                        
                                Young Child PTSD Checklist
                             
                            
                                Free
                             
                            
                                No
                             
                        
                             
                        
                                Young Child PTSD Screen
                             
                            
                                Free
                             
                            
                                No
                             
                        
                             
                        
                                Research Diagnostic Criteria--Preschool Age
                             
                            
                                Free
                             
                            
                                No
                             
                        
                             
                        
                                Adaptation Checklists, Child and Parent Versions
                             
                            
                                Free
                             
                            
                                No
                             
                        
                             
                        
                                Therapist Fidelity Checklist
                             
                            
                                Free
                             
                            
                                No
                             
                        
                             
            
                                Parent Acceptance Checklist
                             
                            
                                Free
                             
                            
                                No